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Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes (Cochrane review)

International Literature

posted by WM Admin on 10 June 2015

In this Cochrane review, the authors assess the impact of Hib and viral Influenza vaccinations during pregnancy on maternal, neonatal and infant health outcomes compared to placebo/control.

Two trials were included this review. One (involving 213 women and 213 neonates) evaluated the impact of Hib vaccination during pregnancy and was assessed as having a 'high risk of bias'. The other study (involving 2116 women and 2049 neonates) evaluated the impact of viral influenza vaccination during pregnancy, and was assessed as being at 'low risk of bias'.

The authors describe the findings from these studies and conclude that "further trials for both Hib and viral influenza vaccines with appropriate study designs and suitable comparison groups are required".

This article is available to read in free full text at:  http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009982.pub2/full

Salam R.A., Das J.K., Dojo Soeandy C., Lassi Z.S., Bhutta Z.A. (2015). Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes. Cochrane Database of Systematic Reviews, 6, CD009982.